R4Q (p.Arg4Gln) variant of LHCGR (P22888)
R4Q (p.Arg4Gln) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
R4Q (p.Arg4Gln) variant details
- p.Arg4Gln
- TOPMed rs889150477
- gnomAD rs889150477
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.11
- CADD 11.20
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available