R26L (p.Arg26Leu) variant of LHCGR (P22888)
R26L (p.Arg26Leu) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
R26L (p.Arg26Leu) variant details
- p.Arg26Leu
- TOPMed rs1670173776
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.11
- CADD 5.21
- PolyPhen-2 0.01
- SIFT 0.65
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available