R112T (p.Arg112Thr) variant of LHCGR (P22888)
R112T (p.Arg112Thr) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R112T (p.Arg112Thr) variant details
- p.Arg112Thr
- ExAC rs768736086
- gnomAD rs768736086
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.14
- CADD 12.30
- PolyPhen-2 0.00
- SIFT 0.97
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available