Q67L (p.Gln67Leu) variant of LHCGR (P22888)
Q67L (p.Gln67Leu) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
Q67L (p.Gln67Leu) variant details
- p.Gln67Leu
- TOPMed rs1190261034
- gnomAD rs1190261034
- Missense
- Variant Prioritization Score for Impact Estimate 0.509
- REVEL 0.42
- CADD 24.30
- PolyPhen-2 0.70
- SIFT 0.63
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available