P31L (p.Pro31Leu) variant of LHCGR (P22888)
P31L (p.Pro31Leu) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
P31L (p.Pro31Leu) variant details
- p.Pro31Leu
- TOPMed rs967924637
- gnomAD rs967924637
- Missense
- Variant Prioritization Score for Impact Estimate 0.679
- REVEL 0.60
- CADD 28.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-05)
- Structural context available