P31H (p.Pro31His) variant of LHCGR (P22888)
P31H (p.Pro31His) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
P31H (p.Pro31His) variant details
- p.Pro31His
- TOPMed rs967924637
- gnomAD rs967924637
- Missense
- Variant Prioritization Score for Impact Estimate 0.675
- REVEL 0.60
- CADD 27.40
- PolyPhen-2 1.00
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 5.6e-05)
- Structural context available