P116A (p.Pro116Ala) variant of LHCGR (P22888)
P116A (p.Pro116Ala) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P116A (p.Pro116Ala) variant details
- p.Pro116Ala
- ESP rs377265035
- ExAC rs377265035
- TOPMed rs377265035
- gnomAD rs377265035
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.16
- CADD 11.80
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the East Asian population (allele frequency 0.00028)
- Structural context available