N99S (p.Asn99Ser) variant of LHCGR (P22888)
N99S (p.Asn99Ser) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
N99S (p.Asn99Ser) variant details
- p.Asn99Ser
- ExAC rs773619386
- gnomAD rs773619386
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.25
- CADD 20.30
- PolyPhen-2 0.08
- SIFT 0.43
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.062)
- Structural context available