N35S (p.Asn35Ser) variant of LHCGR (P22888)
N35S (p.Asn35Ser) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
N35S (p.Asn35Ser) variant details
- p.Asn35Ser
- gnomAD rs1163658646
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.11
- CADD 13.60
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the Latino/Admixed American population (allele frequency 5.6e-05)
- Structural context available