N121K (p.Asn121Lys) variant of LHCGR (P22888)
N121K (p.Asn121Lys) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
N121K (p.Asn121Lys) variant details
- p.Asn121Lys
- TOPMed rs993092773
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.21
- CADD 21.60
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available