L98H (p.Leu98His) variant of LHCGR (P22888)
L98H (p.Leu98His) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L98H (p.Leu98His) variant details
- p.Leu98His
- gnomAD rs1430997827
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.41
- CADD 23.20
- PolyPhen-2 0.94
- SIFT 0.59
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available