L8P (p.Leu8Pro) variant of LHCGR (P22888)
L8P (p.Leu8Pro) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
L8P (p.Leu8Pro) variant details
- p.Leu8Pro
- TOPMed rs1337809465
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.51
- CADD 15.90
- PolyPhen-2 0.10
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available