L86P (p.Leu86Pro) variant of LHCGR (P22888)
L86P (p.Leu86Pro) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
L86P (p.Leu86Pro) variant details
- p.Leu86Pro
- ExAC rs750340960
- TOPMed rs750340960
- gnomAD rs750340960
- Missense
- Variant Prioritization Score for Impact Estimate 0.776
- REVEL 0.87
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available