L42P (p.Leu42Pro) variant of LHCGR (P22888)
L42P (p.Leu42Pro) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
L42P (p.Leu42Pro) variant details
- p.Leu42Pro
- TOPMed rs1670169516
- Missense
- Variant Prioritization Score for Impact Estimate 0.543
- REVEL 0.51
- CADD 24.90
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available