L25R (p.Leu25Arg) variant of LHCGR (P22888)
L25R (p.Leu25Arg) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L25R (p.Leu25Arg) variant details
- p.Leu25Arg
- 1000Genomes rs549032969
- TOPMed rs549032969
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.21
- CADD 20.50
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the 1KG:JPT population (allele frequency 0.0049)
- Structural context available