L111V (p.Leu111Val) variant of LHCGR (P22888)
L111V (p.Leu111Val) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L111V (p.Leu111Val) variant details
- p.Leu111Val
- gnomAD rs1229403196
- Missense
- Variant Prioritization Score for Impact Estimate 0.653
- REVEL 0.77
- CADD 23.90
- PolyPhen-2 0.54
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available