I89T (p.Ile89Thr) variant of LHCGR (P22888)
I89T (p.Ile89Thr) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
I89T (p.Ile89Thr) variant details
- p.Ile89Thr
- ExAC rs763880284
- gnomAD rs763880284
- Missense
- Variant Prioritization Score for Impact Estimate 0.776
- REVEL 0.88
- CADD 25.10
- PolyPhen-2 0.74
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available