I120T (p.Ile120Thr) variant of LHCGR (P22888)
I120T (p.Ile120Thr) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I120T (p.Ile120Thr) variant details
- p.Ile120Thr
- TOPMed rs1237586952
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.12
- CADD 13.70
- PolyPhen-2 0.00
- SIFT 0.84
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available