G40D (p.Gly40Asp) variant of LHCGR (P22888)
G40D (p.Gly40Asp) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
G40D (p.Gly40Asp) variant details
- p.Gly40Asp
- TOPMed rs926321157
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.49
- CADD 24.20
- PolyPhen-2 0.62
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available