G117A (p.Gly117Ala) variant of LHCGR (P22888)
G117A (p.Gly117Ala) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G117A (p.Gly117Ala) variant details
- p.Gly117Ala
- ExAC rs758016158
- gnomAD rs758016158
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.68
- CADD 23.60
- PolyPhen-2 0.75
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available