F119L (p.Phe119Leu) variant of LHCGR (P22888)
F119L (p.Phe119Leu) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
F119L (p.Phe119Leu) variant details
- p.Phe119Leu
- TOPMed rs1650854374
- Missense
- Variant Prioritization Score for Impact Estimate 0.806
- REVEL 0.93
- CADD 25.90
- PolyPhen-2 0.68
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available