D95E (p.Asp95Glu) variant of LHCGR (P22888)
D95E (p.Asp95Glu) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
D95E (p.Asp95Glu) variant details
- p.Asp95Glu
- ExAC rs777195872
- TOPMed rs777195872
- gnomAD rs777195872
- Missense
- Variant Prioritization Score for Impact Estimate 0.539
- REVEL 0.45
- CADD 22.90
- PolyPhen-2 0.60
- SIFT 0.26
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available