D84N (p.Asp84Asn) variant of LHCGR (P22888)
D84N (p.Asp84Asn) in LHCGR (P22888) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes structural context.
D84N (p.Asp84Asn) variant details
- p.Asp84Asn
- rs200707752
- NCI-TCGA Cosmic COSV9968
- cosmic curated COSV99683
- gnomAD rs200707752
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.668
- AlphaMissense 0.36
- MetaLR 0.81
- MetaSVM 0.76
- PolyPhen-2 1.00
- SIFT 0.31
- EVE 0.29
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available