D84H (p.Asp84His) variant of LHCGR (P22888)
D84H (p.Asp84His) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
D84H (p.Asp84His) variant details
- p.Asp84His
- gnomAD rs200707752
- Missense
- Variant Prioritization Score for Impact Estimate 0.682
- REVEL 0.78
- AlphaMissense 0.36
- MetaLR 0.81
- MetaSVM 0.76
- CADD 24.40
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available