D84E (p.Asp84Glu) variant of LHCGR (P22888)
D84E (p.Asp84Glu) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
D84E (p.Asp84Glu) variant details
- p.Asp84Glu
- ExAC rs760722768
- TOPMed rs760722768
- gnomAD rs760722768
- Missense
- Variant Prioritization Score for Impact Estimate 0.567
- REVEL 0.61
- CADD 22.10
- PolyPhen-2 0.67
- SIFT 0.58
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available