Y64H (p.Tyr64His) variant of LEPR (Leptin receptor)
Y64H (p.Tyr64His) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
Y64H (p.Tyr64His) variant details
- p.Tyr64His
- TOPMed rs1484674491
- gnomAD rs1484674491
- Missense
- Variant Prioritization Score for Impact Estimate 0.0683
- REVEL 0.05
- CADD 4.24
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available