V8V (p.Val8Val) variant of LEPR (Leptin receptor)
V8V (p.Val8Val) in LEPR (Leptin receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
V8V (p.Val8Val) variant details
- p.Val8Val
- gnomAD 1-65565589-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.394
- CADD 15.80
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available