T77A (p.Thr77Ala) variant of LEPR (Leptin receptor)
T77A (p.Thr77Ala) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
T77A (p.Thr77Ala) variant details
- p.Thr77Ala
- Ensembl rs766147770
- Missense
- Variant Prioritization Score for Impact Estimate 0.0535
- REVEL 0.05
- CADD 0.47
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available