T57I (p.Thr57Ile) variant of LEPR (Leptin receptor)
T57I (p.Thr57Ile) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
T57I (p.Thr57Ile) variant details
- p.Thr57Ile
- gnomAD 1-65570602-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.09
- CADD 3.27
- PolyPhen-2 0.28
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available