T29P (p.Thr29Pro) variant of LEPR (Leptin receptor)
T29P (p.Thr29Pro) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T29P (p.Thr29Pro) variant details
- p.Thr29Pro
- ExAC rs749087675
- gnomAD rs749087675
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.04
- CADD 3.08
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available