T29A (p.Thr29Ala) variant of LEPR (Leptin receptor)
T29A (p.Thr29Ala) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T29A (p.Thr29Ala) variant details
- p.Thr29Ala
- ExAC rs749087675
- gnomAD rs749087675
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.02
- CADD 7.19
- PolyPhen-2 0.07
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available