T20N (p.Thr20Asn) variant of LEPR (Leptin receptor)
T20N (p.Thr20Asn) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T20N (p.Thr20Asn) variant details
- p.Thr20Asn
- Ensembl rs932745822
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.14
- CADD 22.70
- PolyPhen-2 0.55
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available