S36Y (p.Ser36Tyr) variant of LEPR (Leptin receptor)
S36Y (p.Ser36Tyr) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S36Y (p.Ser36Tyr) variant details
- p.Ser36Tyr
- ExAC rs772735713
- gnomAD rs772735713
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.07
- CADD 21.60
- PolyPhen-2 0.23
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available