S25A (p.Ser25Ala) variant of LEPR (Leptin receptor)
S25A (p.Ser25Ala) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
S25A (p.Ser25Ala) variant details
- p.Ser25Ala
- gnomAD 1-65570505-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.09
- CADD 6.41
- PolyPhen-2 0.00
- SIFT 0.81
- Population evidence available
- Structural context available
- Literature evidence available