R32G (p.Arg32Gly) variant of LEPR (Leptin receptor)
R32G (p.Arg32Gly) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
R32G (p.Arg32Gly) variant details
- p.Arg32Gly
- gnomAD 1-65570526-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.10
- CADD 22.10
- PolyPhen-2 0.06
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available