P39L (p.Pro39Leu) variant of LEPR (Leptin receptor)
P39L (p.Pro39Leu) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P39L (p.Pro39Leu) variant details
- p.Pro39Leu
- Ensembl rs1654083227
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.12
- CADD 16.80
- PolyPhen-2 0.01
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available