N81D (p.Asn81Asp) variant of LEPR (Leptin receptor)
N81D (p.Asn81Asp) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
N81D (p.Asn81Asp) variant details
- p.Asn81Asp
- ExAC rs772680635
- TOPMed rs772680635
- gnomAD rs772680635
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.08
- CADD 4.89
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available