N61S (p.Asn61Ser) variant of LEPR (Leptin receptor)
N61S (p.Asn61Ser) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
N61S (p.Asn61Ser) variant details
- p.Asn61Ser
- ESP rs370723424
- ExAC rs370723424
- TOPMed rs370723424
- gnomAD rs370723424
- Missense
- Variant Prioritization Score for Impact Estimate 0.0772
- REVEL 0.04
- CADD 0.43
- PolyPhen-2 0.00
- SIFT 0.87
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available