N23S (p.Asn23Ser) variant of LEPR (Leptin receptor)
N23S (p.Asn23Ser) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
N23S (p.Asn23Ser) variant details
- p.Asn23Ser
- gnomAD rs1487793938
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.09
- CADD 12.30
- PolyPhen-2 0.02
- SIFT 0.50
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available