N23K (p.Asn23Lys) variant of LEPR (Leptin receptor)
N23K (p.Asn23Lys) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
N23K (p.Asn23Lys) variant details
- p.Asn23Lys
- ExAC rs758614103
- TOPMed rs758614103
- gnomAD rs758614103
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.04
- CADD 3.62
- PolyPhen-2 0.12
- SIFT 0.22
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available