M38L (p.Met38Leu) variant of LEPR (Leptin receptor)
M38L (p.Met38Leu) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
M38L (p.Met38Leu) variant details
- p.Met38Leu
- Ensembl rs574850620
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.10
- CADD 13.20
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the South Asian population (allele frequency 4.6e-05)
- Structural context available