K5N (p.Lys5Asn) variant of LEPR (Leptin receptor)
K5N (p.Lys5Asn) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
K5N (p.Lys5Asn) variant details
- p.Lys5Asn
- ExAC rs780405424
- TOPMed rs780405424
- gnomAD rs780405424
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.09
- CADD 19.30
- PolyPhen-2 0.23
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available