K55T (p.Lys55Thr) variant of LEPR (Leptin receptor)
K55T (p.Lys55Thr) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
K55T (p.Lys55Thr) variant details
- p.Lys55Thr
- gnomAD 1-65570596-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0994
- REVEL 0.04
- CADD 6.66
- PolyPhen-2 0.12
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available