K34M (p.Lys34Met) variant of LEPR (Leptin receptor)
K34M (p.Lys34Met) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
K34M (p.Lys34Met) variant details
- p.Lys34Met
- gnomAD 1-65570533-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.13
- CADD 22.30
- PolyPhen-2 0.55
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available