I19T (p.Ile19Thr) variant of LEPR (Leptin receptor)
I19T (p.Ile19Thr) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
I19T (p.Ile19Thr) variant details
- p.Ile19Thr
- gnomAD 1-65570488-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.05
- CADD 11.70
- PolyPhen-2 0.00
- SIFT 0.38
- Population evidence available
- Structural context available
- Literature evidence available