I16M (p.Ile16Met) variant of LEPR (Leptin receptor)
I16M (p.Ile16Met) in LEPR (Leptin receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
I16M (p.Ile16Met) variant details
- p.Ile16Met
- gnomAD 1-65570473-AATTT-
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.431
- CADD 25.50
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available