H63R (p.His63Arg) variant of LEPR (Leptin receptor)
H63R (p.His63Arg) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
H63R (p.His63Arg) variant details
- p.His63Arg
- ExAC rs781329053
- gnomAD rs781329053
- Missense
- Variant Prioritization Score for Impact Estimate 0.0481
- REVEL 0.04
- CADD 0.07
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.0014)
- Structural context available