H12R (p.His12Arg) variant of LEPR (Leptin receptor)
H12R (p.His12Arg) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
H12R (p.His12Arg) variant details
- p.His12Arg
- TOPMed rs1465098791
- gnomAD rs1465098791
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.01
- CADD 8.18
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available