G76S (p.Gly76Ser) variant of LEPR (Leptin receptor)
G76S (p.Gly76Ser) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
G76S (p.Gly76Ser) variant details
- p.Gly76Ser
- gnomAD 1-65570658-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.04
- CADD 8.20
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available