G62R (p.Gly62Arg) variant of LEPR (Leptin receptor)
G62R (p.Gly62Arg) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
G62R (p.Gly62Arg) variant details
- p.Gly62Arg
- gnomAD 1-65570616-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.10
- CADD 19.00
- PolyPhen-2 0.02
- SIFT 0.21
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available